Source: MRI Imaging Media
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS), with the pathological feature being demyelinating lesions in the white matter of the brain and spinal cord. In addition to motor disorders, the abnormal mental symptoms of MS patients provide new insights into the pathophysiology of the disease. Depression is a chronic mental disorder characterized by persistent loss of pleasure and a low mood. Studies have shown that the incidence of depression in China is increasing year by year, with a high incidence rate. The depressive state is one of the main determinants of the quality of life of MS patients, affecting their adherence to treatment, and severe depression can lead MS patients to have suicidal intentions. Due to the heterogeneity of the pathophysiological mechanisms and the limitations of detection methods, the pathogenesis of depressed MS (DMS) is not yet clear. With the development of neuroimaging technology, MRI has significant advantages in detecting psychiatric disorders.
Professor Li Xianglin’s team at the Binzhou Medical College School of Medical Imaging will review the research progress of multimodal MRI technology in DMS, aiming to find biological markers of abnormal brain structure and function in DMS, and to provide imaging evidence for the pathophysiological mechanism of DMS.
This project is supported by the National Natural Science Foundation of China (62176181) and the Shandong Provincial Natural Science Foundation Project (ZR2022MH118).
[Qi Kai, Li Hao, Xu Junhai, et al. Research Progress of Multimodal MRI Technology in Multiple Sclerosis Combined with Depression[J]. MRI Imaging, 2024, 15(6):144-148.
DOI: 10.12015/issn.1674-8034.2024.06.022]
(Authors: Qi Kai, Li Hao, Xu Junhai, Ren Rui, Li Xianglin)
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Professor Li Xianglin
Li Xianglin, MD, Professor, Dean of the School of Medical Imaging, Binzhou Medical College.
Specialties: Molecular imaging and brain functional MR imaging.
Education background: MD, major in imaging medicine and medicine.
Social affiliations: Committee member of the 16th Molecular Imaging Group of the Chinese Medical Association Radiology Branch, Vice-Chairman of the 9th Education Group of the Imaging Technology Branch of the Chinese Medical Association, Deputy Chairman of the 11th Molecular Imaging Group of the Shandong Provincial Medical Association Radiology Branch, Deputy Chairman of the 7th Medical Education Group of the Shandong Provincial Medical Association Radiology Technology Branch, Deputy Director of the Imaging Medicine Professional Committee of the Shandong Health Management Association, Deputy Director of the Medical Imaging Innovation and Research Branch of the Shandong Research Hospital Association.
Awards/Honors: One third prize of scientific and technological progress in Shandong Province, two third prizes of outstanding scientific research achievements in universities in Shandong Province, and the 2021 Outstanding Supervisor of Postgraduates in Shandong Province.
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Editor: Jiang Jun
Initial Review: Zhang Qin
Secondary Review: Wang Zhiqiang
Final Review: He Guangjun
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