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Tuesday, May 6, 2025

Loss of Sexual Desire After Stopping Antidepressants!

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Side effects of antidepressants are not unfamiliar, among which sexual dysfunction is particularly troublesome for many patients. Decreased libido, weak orgasms, and even numbness in the genitals are issues that many patients find unbearable. Recently, more and more voices have emerged online, revealing a more enduring and distressing side effect – even after stopping the medication, these sexual problems persist.

Persistent sexual distress: the real voices of patients

According to The New York Times, 27-year-old Emily Grey from Vancouver, Canada, took the antidepressant Celexa between the ages of 17 and 23. Even after years of stopping the medication, her sexual function remains severely affected. “My clitoris feels like a joint, which is not normal at all.” Emily’s story is not unique, as more and more patients face similar troubles after discontinuing selective serotonin reuptake inhibitors (S.S.R.I.).

Prozac, as one of the most common S.S.R.I.’s, explicitly states on its safety label that persistent sexual problems may occur after discontinuation. Health agencies in Europe and Canada also acknowledge that these drugs may lead to long-term sexual dysfunction.

Scientific controversy and exploration

Despite more patients reporting sexual dysfunction after discontinuation, the medical community still debates this issue. Some psychiatrists believe that these symptoms may be related to a recurrence of depression rather than long-term issues caused by the drugs themselves.

Dr. Anita Clayton, Director of Psychiatry at the University of Virginia School of Medicine, stated, “I believe this is a recurrence of depression until proven otherwise.” While she acknowledges the wide-ranging sexual side effects of S.S.R.I.’s, she is also concerned that too much focus on this seemingly rare side effect may discourage patients with suicidal tendencies from trying antidepressants.

However, researchers have begun searching for evidence. An Israeli study found that in males who discontinued S.S.R.I.’s, about 1 in 216 later required treatment for erectile dysfunction, a threefold increase compared to the general population.

Patient self-awareness and online support

With the widespread use of S.S.R.I.’s, especially among adolescents, more patients are realizing the profound impact these medications may have on their sexual function. In the absence of medical support, many patients turn to the internet for help and support.

For example, a discussion group on Reddit grew from 750 members in 2020 to around 10,000 members today. These patients not only share their experiences but also actively advocate for warnings to be added to drug labels.

Roy Whaley, 38, from the UK, briefly used the antidepressant Citalopram at the age of 22. Now, 16 years later, his libido has almost completely disappeared, and his genitals feel numb as if injected with an anesthetic. “This is not just a sexual issue, it’s a fundamental change in how I experience life,” Whaley expressed.

Conclusion: Approach medication choices carefully

Antidepressants can indeed help many patients overcome psychological difficulties, but the potential long-term side effects should not be overlooked. For patients currently taking or considering antidepressants, thorough communication with a doctor, understanding the potential risks of the medication, and seeking alternative treatments when necessary are crucial steps.

The sexual side effects of antidepressants deserve further exploration and attention. Through scientific research and patient self-awareness, it may be possible in the future to better understand and address these troubles, allowing more patients to overcome depression without being burdened by sexual function issues.

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