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Husband and wife sharing a bed for 5 years discover that the husband’s chromosome is female, sparking social attention and discussion.

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In Guangzhou, an ordinary family is facing a rare medical challenge. Xiao Liu (pseudonym) and her husband have been married for five years, and their life has always been filled with harmony and love. However, after five years, their life has not been able to welcome the fruit of love as desired. After hospital examinations, they discovered a shocking fact – Xiao Liu’s husband is not a biological male.

In our daily lives, we often judge a person’s gender based on their phenotypic features. However, as pointed out by doctors, a person’s gender is not solely determined by phenotype. Gender can be classified into chromosomal gender, gonadal gender, and phenotypic gender. Although Xiao Liu’s husband appears male in phenotype and gonads, and his self-identification is male, his chromosomal gender is female “46, XX”. This condition is medically known as “46, XX male syndrome”.

“46, XX male syndrome” is a rare congenital intersex genetic disorder, affecting one in every 20,000 males. However, treatment approaches for this condition vary from individual to individual. Some patients may only require symptomatic treatment to improve their quality of life. For patients with fertility needs, assisted reproductive technologies such as sperm donation and artificial insemination can help them achieve parenthood.

For Xiao Liu and her husband, they are now facing the challenge of accepting this fact. They need to reassess their relationship, redefine their family, and reconsider their future.

This story showcases the miracle of medicine and reveals the complexity of human gender perception. We hope that Xiao Liu and her husband can find their own path in this process and that medicine can offer them more possibilities for the future.

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