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Tuesday, May 6, 2025

Ankylosing spondylitis, a hidden and complex disease

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In the realm of young men’s health, ankylosing spondylitis lurks like a silent enemy, stealthily attacking their spines, gradually depriving them of their mobility and quality of life. This article aims to delve into the various symptoms of this disease, revealing its hidden and complex nature, with the goal of increasing public awareness and vigilance.

Hidden Prelude: Morning Stiffness and Lower Back Pain

The initial symptoms of ankylosing spondylitis are often hard to detect, with the most typical being lower back pain accompanied by morning stiffness. This pain is particularly noticeable after long periods of lying down at night or sitting during the day. When getting up in the morning, patients feel stiffness in their lower back, as if bound by an invisible lock, which gradually eases with movement. However, as the condition progresses, this morning stiffness becomes more severe, and the duration lengthens over time.

Progressive Invasion: Restricted Mobility and Deformity

If the disease is not promptly controlled, it will further erode the patient’s spine. The lower back pain intensifies, the range of motion in various directions of the lumbar spine significantly diminishes, thoracic mobility decreases, making it difficult for patients to perform everyday movements such as bending over or turning. More severely, with the progressive stiffness from the bottom up in the spine, the lumbar lordosis disappears, excessive thoracic kyphosis occurs, eventually forming a “bamboo-like” spine, leading to a prominent hunchback deformity. Additionally, hip joint flexion contractures are also common symptoms in the later stages, where patients exhibit a distinctive fixed gait while walking, and the knee joints are forced to maintain a certain degree of flexion.

Warnings Beyond Joints: Multi-System Involvement

Ankylosing spondylitis not only affects the spine but also involves peripheral joints and multiple organs. Enthesitis is a common manifestation, especially in the heel, where patients may experience unbearable heel pain. Ocular manifestations should not be overlooked, as acute anterior uveitis or conjunctivitis may cause redness and blurred vision in both eyes. Cardiac manifestations such as aortic arch expansion, abnormal cardiac conduction systems, although uncommon, can severely threaten the patient’s life if they occur. Furthermore, some patients may also experience systemic symptoms such as renal dysfunction, interstitial pneumonia, and so on.

Dual Challenge of Genetics and Environment

The pathogenesis of ankylosing spondylitis is complex, with genetic factors playing a significant role. HLA-B27 positivity is considered an important genetic marker for ankylosing spondylitis, significantly increasing the risk of the disease in positive individuals. However, environmental factors should not be ignored, as infectious diseases, trauma, overwork, cold, and dampness can all act as “catalysts” that trigger or exacerbate the condition.

Early Intervention: Key to Protecting the Spine

In the face of the invasion of ankylosing spondylitis, early detection, diagnosis, and treatment are crucial. Once lower back pain with morning stiffness appears, especially if the back pain worsen after prolonged sitting or facing difficulty turning over at night, immediate medical attention and professional examination are warranted. Through comprehensive approaches such as medication, functional exercises, physical therapy, the disease progression can be effectively controlled, delaying its advancement and improving the patient’s quality of life.

In conclusion, ankylosing spondylitis is a hidden and complex disease with diverse symptoms involving multiple systems. Only by raising awareness and intervening promptly can we take the initiative in this battle against the enemy of spinal guardians, safeguarding our health and freedom.

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