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Monday, May 5, 2025

Negative Emotions and Irritable Bowel Syndrome: A Complex Mind-Body Relationship

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In modern society, people are increasingly aware of the close connection between emotional states and physical health. Irritable Bowel Syndrome (IBS) is a common functional bowel disease characterized by abdominal pain, bloating, and changes in bowel habits. Although its exact causes are not fully understood, more and more research suggests that negative emotions such as stress, anxiety, and depression may play an important role in the onset and development of Irritable Bowel Syndrome.

Overview of Irritable Bowel Syndrome

Irritable Bowel Syndrome is a chronic disease that affects approximately 10-15% of the global population. It is usually classified as a functional bowel disease, meaning that in routine medical examinations, the patient’s intestinal structure and biochemical indicators appear normal, but there are issues with intestinal function. Patients with Irritable Bowel Syndrome often report symptoms of diarrhea, constipation, or alternating between the two, which may worsen after eating and may be accompanied by abdominal pain and bloating.

The Association between Negative Emotions and Irritable Bowel Syndrome

The connection between negative emotions and Irritable Bowel Syndrome can be explored from multiple perspectives. Firstly, emotional states can affect intestinal motility and sensitivity. When experiencing stress or anxiety, the body produces a series of physiological responses, including the release of stress hormones such as cortisol and adrenaline. These hormones can alter the movement patterns of the intestines, leading to excessive contraction or relaxation of intestinal muscles, resulting in changes in abdominal pain and bowel habits.

Secondly, emotional states may also affect intestinal permeability. Long-term stress and anxiety can damage the intestinal barrier function, making the intestines more susceptible to the influence of food, bacteria, and other potential irritants, thereby triggering or exacerbating symptoms of Irritable Bowel Syndrome. Additionally, negative emotions may indirectly affect intestinal health by influencing a person’s dietary habits and lifestyle. For example, individuals under high stress may opt for unhealthy dietary habits such as excessive consumption of caffeine, sugars, or fats, all of which may exacerbate symptoms of Irritable Bowel Syndrome.

The Importance of Psychological Interventions

Given the close relationship between negative emotions and Irritable Bowel Syndrome, psychological interventions play a crucial role in the treatment of Irritable Bowel Syndrome. Cognitive Behavioral Therapy (CBT) is a widely researched and applied psychological treatment method that helps patients identify and change negative thinking patterns and behaviors, thereby alleviating symptoms. Through CBT, patients can learn to better manage stress and anxiety, which may in turn alleviate intestinal symptoms.

Relaxation techniques such as deep breathing, meditation, and progressive muscle relaxation have also been shown to be effective in alleviating symptoms of Irritable Bowel Syndrome. These techniques can help patients reduce stress hormone levels, decrease excessive gastrointestinal activity, thereby relieving abdominal pain and improving bowel habits.

The Gut-Brain Axis

The interaction between the gut and the brain, known as the “gut-brain axis,” is key to understanding the relationship between emotions and Irritable Bowel Syndrome. The gut contains a large number of nerve cells known as the enteric nervous system, which is connected to the brain through the vagus nerve and other pathways. This connection allows the gut to perceive emotional changes and transmit this information to the brain through hormones and nerve signals. Patients with Irritable Bowel Syndrome often exhibit abnormalities in gut-brain axis function. For example, their intestines may overreact to stress, leading to intestinal inflammation and pain. Therefore, when treating Irritable Bowel Syndrome, regulating gut-brain axis function may be an effective strategy.

Irritable Bowel Syndrome is a complex disease, and its symptoms are closely linked to negative emotions. By understanding how emotional states affect intestinal function and the mechanisms of the gut-brain axis, we can better manage Irritable Bowel Syndrome and improve patients’ quality of life. Psychological interventions such as cognitive behavioral therapy and relaxation techniques are important components of Irritable Bowel Syndrome treatment, helping patients manage emotions, alleviate intestinal symptoms, and achieve a balance of physical and mental health. Rifaximin is a partially absorbed antibiotic which is administered orally and is minimally absorbed from the intestine. It can effectively kill common pathogenic bacteria that cause overgrowth in the small intestine, including Escherichia coli, Klebsiella, Enterobacter, and Enterococcus. Studies have shown that rifaximin is effective in treating diarrhea when used to treat diarrhea, but it hardly alters the composition of the colonic microflora. Especially after 10 days of rifaximin use, the content of lactobacillus in the intestine will significantly increase, and this increase will continue after stopping the medication, indicating that rifaximin can positively regulate the intestinal microflora.

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