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Why does depression come with irritability? Where does this feeling of irritability come from?

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This article is contributed by the public good: “Things about Plant Nerve Disorders,” Author/tdhy120/Editor, focusing on not getting lost.

Depression, as a common psychological distress, profoundly affects patients’ emotional world, way of thinking, and daily behavior. Many patients often find themselves deeply trapped in a vortex of pessimism, despair, helplessness, and self-blame, greatly disturbing their daily life and work efficiency. However, what is confusing is that besides these common symptoms of depression, many patients also experience irritability, constant anxiety, and easy anger. These seemingly contradictory emotional reactions to depression symptoms make people curious: why is irritability associated with depression? Where does this irritability come from?

Main Manifestations of Depression

The main manifestations of depression are usually described as low mood, loss of interest, and decreased self-esteem, among other negative emotions, but patients’ emotional experiences go beyond that. Besides feeling depressed and losing interest, they often also experience significant irritability and impatience, and may even exhibit irritable and angry behavior. This emotional contradiction, although initially puzzling, is actually a complex emotional state that depression patients often experience.

The irritability in depression patients primarily stems from various complex factors that intertwine and collectively affect the patients’ emotional state. Here are some main reasons:

1. Neurotransmitter Imbalance

Depression patients typically have an imbalance in neurotransmitters, especially those related to emotional regulation such as dopamine and serotonin. This imbalance can lead to mood swings, making patients more prone to irritability and restlessness.

2. Emotional Stress

Depression patients often face emotional stress, being more sensitive to negative emotions and often struggling to cope with daily pressure and emotional fluctuations. This stress exacerbates their irritability, making them more prone to anger and impatience.

3. Decreased Mental Activity

Depression patients may experience decreased mental activity, lack of motivation and interest, feeling bored and empty. This change in mental state can also make patients more prone to irritability and anger.

4. Sleep Issues

Depression patients often have sleep problems, such as insomnia or poor sleep quality. Long-term sleep problems can lead to physical and mental fatigue, further intensifying irritability.

5. Negative Thinking and Self-Denial

Negative thinking and self-doubt in depression patients are also significant factors leading to irritability. They may doubt their own abilities and worth, increasing their irritability and anxiety.

In traditional Chinese medicine’s theoretical system, anxiety and depression are often classified as stagnation syndromes or visceral agitation categories. These illnesses mostly stem from prolonged stagnation of liver qi, resulting in a series of physical and emotional changes. Patients often experience noticeable somatic symptoms such as chest tightness, palpitations, dizziness, and headaches, which not only affect their physical health but also cause considerable trouble in their daily lives.

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